Methylglyoxal-derived posttranslational arginine modifications are abundant histone marks

Histone posttranslational modifications (PTMs) regulate chromatin dynamics, DNA accessibility, and transcription to expand the genetic code. Many of these PTMs are produced through cellular metabolism to offer both feedback and feedforward regulation. Herein we describe the existence of Lys and Arg...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Galligan, James J., Wepy, James A., Streeter, Matthew D., Kingsley, Philip J., Mitchener, Michelle M., Wauchope, Orrette R., Beavers, William N., Rose, Kristie L., Wang, Tina, Spiegel, David A., Marnett, Lawrence J.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2018
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6140490/
https://ncbi.nlm.nih.gov/pubmed/30150385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1802901115
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