Methylglyoxal-derived posttranslational arginine modifications are abundant histone marks

Histone posttranslational modifications (PTMs) regulate chromatin dynamics, DNA accessibility, and transcription to expand the genetic code. Many of these PTMs are produced through cellular metabolism to offer both feedback and feedforward regulation. Herein we describe the existence of Lys and Arg...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Galligan, James J., Wepy, James A., Streeter, Matthew D., Kingsley, Philip J., Mitchener, Michelle M., Wauchope, Orrette R., Beavers, William N., Rose, Kristie L., Wang, Tina, Spiegel, David A., Marnett, Lawrence J.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2018
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6140490/
https://ncbi.nlm.nih.gov/pubmed/30150385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1802901115
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