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Exploring Post-Translational Arginine Modification Using Chemically Synthesized Methylglyoxal Hydroimidazolones (MG-Hs)

The methylglyoxal-derived hydroimidazolones (MG-Hs, Figure 1A) comprise the most prevalent class of non-enzymatic, post-translational modifications of protein arginine residues found in nature. These adducts form spontaneously in the human body, and are also present at high levels in the human diet....

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Main Authors: Wang, Tina, Kartika, Rendy, Spiegel, David A.
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3397831/
https://ncbi.nlm.nih.gov/pubmed/22591136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja301994d
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