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Modulating the modulators: regulation of protein arginine methyltransferases by post-translational modifications

The therapeutic potential of targeting protein arginine methyltransferases (PRMTs) is inextricably linked to their key roles in various cellular functions, including splicing, proliferation, cell cycle regulation, differentiation, and DNA damage signaling. Unsurprisingly, the development of inhibito...

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Detalhes bibliográficos
Publicado no:Drug Discov Today
Main Authors: Hartley, Antja-Voy, Lu, Tao
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7572788/
https://ncbi.nlm.nih.gov/pubmed/32629172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drudis.2020.06.031
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