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Regulation of protein stability of DNA methyltransferase 1 by post-translational modifications

DNA methylation is an important epigenetic mechanism that ensures correct gene expression and maintains genetic stability. DNA methyltransferase 1 (DNMT1) is the primary enzyme that maintains DNA methylation during replication. Dysregulation of DNMT1 is implicated in a variety of diseases. DNMT1 pro...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Scott, Anthony, Song, Jing, Ewing, Rob, Wang, Zhenghe
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3932833/
https://ncbi.nlm.nih.gov/pubmed/24389641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/abbs/gmt146
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