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Compensatory increases of select proteostasis networks after Hsp70 inhibition in cancer cells
Cancer cells thrive when challenged with proteotoxic stress by inducing components of the protein folding, proteasome, autophagy and unfolded protein response (UPR) pathways. Consequently, specific molecular chaperones have been validated as targets for anti-cancer therapies. For example, inhibition...
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| Publicado no: | J Cell Sci |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Company of Biologists Ltd
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6140321/ https://ncbi.nlm.nih.gov/pubmed/30131440 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.217760 |
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