The Dimer-of-Trimers Assembly Prevents Catalysis at the Transferase Site of Prokaryotic FAD Synthase

Flavin mononucleotide (FMN) and flavin-adenine dinucleotide (FAD) are essential flavoprotein cofactors. A riboflavin kinase (RFK) activity catalyzes riboflavin phosphorylation to FMN, which can then be transformed into FAD by an FMN:adenylyltransferase (FMNAT) activity. Two enzymes are responsible f...

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Detalles Bibliográficos
Publicado en:Biophys J
Main Authors: Lans, Isaias, Seco, Juan, Serrano, Ana, Burbano, Ricardo, Cossio, Pilar, Daza, Martha C., Medina, Milagros
Formato: Artigo
Idioma:Inglês
Publicado: The Biophysical Society 2018
Assuntos:
Proteins
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6139884/
https://ncbi.nlm.nih.gov/pubmed/30177440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2018.08.011
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