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In silico discovery and biological validation of ligands of FAD synthase, a promising new antimicrobial target

New treatments for diseases caused by antimicrobial-resistant microorganisms can be developed by identifying unexplored therapeutic targets and by designing efficient drug screening protocols. In this study, we have screened a library of compounds to find ligands for the flavin-adenine dinucleotide...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Lans, Isaias, Anoz-Carbonell, Ernesto, Palacio-Rodríguez, Karen, Aínsa, José Antonio, Medina, Milagros, Cossio, Pilar
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7449411/
https://ncbi.nlm.nih.gov/pubmed/32797038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1007898
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