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Discovery of antimicrobial compounds targeting bacterial type FAD synthetases

The increase of bacterial strains resistant to most of the available antibiotics shows a need to explore novel antibacterial targets to discover antimicrobial drugs. Bifunctional bacterial FAD synthetases (FADSs) synthesise the flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD). These...

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Publicat a:J Enzyme Inhib Med Chem
Autors principals: Sebastián, María, Anoz-Carbonell, Ernesto, Gracia, Begoña, Cossio, Pilar, Aínsa, José Antonio, Lans, Isaías, Medina, Milagros
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7012052/
https://ncbi.nlm.nih.gov/pubmed/29258359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2017.1411910
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