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Interaction between DUE-B and Treslin is required to load Cdc45 on chromatin in human cells
A key step in the initiation of eukaryotic DNA replication is the binding of the activator protein Cdc45 to promote MCM helicase unwinding of the origin template. We show here that the c-myc origin DNA unwinding element-binding protein, DUE-B, interacts in HeLa cells with the replication initiation...
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| Publicat a: | J Biol Chem |
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| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Biochemistry and Molecular Biology
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6139568/ https://ncbi.nlm.nih.gov/pubmed/30037903 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.004519 |
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