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Dynamic relocalization of replication origins by Fkh1 requires execution of DDK function and Cdc45 loading at origins

Chromosomal DNA elements are organized into spatial domains within the eukaryotic nucleus. Sites undergoing DNA replication, high-level transcription, and repair of double-strand breaks coalesce into foci, although the significance and mechanisms giving rise to these dynamic structures are poorly un...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Zhang, Haiyang, Petrie, Meghan V, He, Yiwei, Peace, Jared M, Chiolo, Irene E, Aparicio, Oscar M
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6533057/
https://ncbi.nlm.nih.gov/pubmed/31084713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.45512
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