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Dynamic relocalization of replication origins by Fkh1 requires execution of DDK function and Cdc45 loading at origins

Chromosomal DNA elements are organized into spatial domains within the eukaryotic nucleus. Sites undergoing DNA replication, high-level transcription, and repair of double-strand breaks coalesce into foci, although the significance and mechanisms giving rise to these dynamic structures are poorly un...

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Библиографические подробности
Опубликовано в: :eLife
Главные авторы: Zhang, Haiyang, Petrie, Meghan V, He, Yiwei, Peace, Jared M, Chiolo, Irene E, Aparicio, Oscar M
Формат: Artigo
Язык:Inglês
Опубликовано: eLife Sciences Publications, Ltd 2019
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6533057/
https://ncbi.nlm.nih.gov/pubmed/31084713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.45512
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