Dynamic relocalization of replication origins by Fkh1 requires execution of DDK function and Cdc45 loading at origins

Chromosomal DNA elements are organized into spatial domains within the eukaryotic nucleus. Sites undergoing DNA replication, high-level transcription, and repair of double-strand breaks coalesce into foci, although the significance and mechanisms giving rise to these dynamic structures are poorly un...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:eLife
Prif Awduron: Zhang, Haiyang, Petrie, Meghan V, He, Yiwei, Peace, Jared M, Chiolo, Irene E, Aparicio, Oscar M
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: eLife Sciences Publications, Ltd 2019
Pynciau:
Chromosomes and Gene Expression
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6533057/
https://ncbi.nlm.nih.gov/pubmed/31084713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.45512
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