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The DNA Unwinding Element Binding Protein DUE-B Interacts with Cdc45 in Preinitiation Complex Formation

Template unwinding during DNA replication initiation requires the loading of the MCM helicase activator Cdc45 at replication origins. We show that Cdc45 interacts with the DNA unwinding element (DUE) binding protein DUE-B and that these proteins localize to the DUEs of active replication origins. DU...

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Autori principali: Chowdhury, A., Liu, G., Kemp, M., Chen, X., Katrangi, N., Myers, S., Ghosh, M., Yao, J., Gao, Y., Bubulya, P., Leffak, M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2832489/
https://ncbi.nlm.nih.gov/pubmed/20065034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00710-09
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