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A requirement for MCM7 and Cdc45 in chromosome unwinding during eukaryotic DNA replication
In vertebrates, MCM2–7 and Cdc45 are required for DNA replication initiation, but it is unknown whether they are also required for elongation, as in yeast. Moreover, although MCM2–7 is a prime candidate for the eukaryotic replicative DNA helicase, a demonstration that MCM2–7 unwinds DNA during repli...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2004
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC517609/ https://ncbi.nlm.nih.gov/pubmed/15329670 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600369 |
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