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A requirement for MCM7 and Cdc45 in chromosome unwinding during eukaryotic DNA replication

In vertebrates, MCM2–7 and Cdc45 are required for DNA replication initiation, but it is unknown whether they are also required for elongation, as in yeast. Moreover, although MCM2–7 is a prime candidate for the eukaryotic replicative DNA helicase, a demonstration that MCM2–7 unwinds DNA during repli...

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Hlavní autoři: Pacek, Marcin, Walter, Johannes C
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2004
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC517609/
https://ncbi.nlm.nih.gov/pubmed/15329670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600369
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