Increased urinary angiotensin converting enzyme 2 and neprilysin in patients with type 2 diabetes

Angiotensin converting enzyme 2 (ACE2) and neprilysin (NEP) are metalloproteases that are highly expressed in the renal proximal tubules. ACE2 and NEP generate renoprotective angiotensin (1–7) from angiotensin II and angiotensin I, respectively, and therefore could have a major role in chronic kidne...

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Udgivet i:Am J Physiol Renal Physiol
Main Authors: Gutta, Sridevi, Grobe, Nadja, Kumbaji, Meenasri, Osman, Hassan, Saklayen, Mohammad, Li, Gengxin, Elased, Khalid M.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6139527/
https://ncbi.nlm.nih.gov/pubmed/29561187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00565.2017
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