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Increased urinary angiotensin converting enzyme 2 and neprilysin in patients with type 2 diabetes

Angiotensin converting enzyme 2 (ACE2) and neprilysin (NEP) are metalloproteases that are highly expressed in the renal proximal tubules. ACE2 and NEP generate renoprotective angiotensin (1–7) from angiotensin II and angiotensin I, respectively, and therefore could have a major role in chronic kidne...

詳細記述

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書誌詳細
出版年:Am J Physiol Renal Physiol
主要な著者: Gutta, Sridevi, Grobe, Nadja, Kumbaji, Meenasri, Osman, Hassan, Saklayen, Mohammad, Li, Gengxin, Elased, Khalid M.
フォーマット: Artigo
言語:Inglês
出版事項: American Physiological Society 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6139527/
https://ncbi.nlm.nih.gov/pubmed/29561187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00565.2017
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