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Increased urinary angiotensin converting enzyme 2 and neprilysin in patients with type 2 diabetes

Angiotensin converting enzyme 2 (ACE2) and neprilysin (NEP) are metalloproteases that are highly expressed in the renal proximal tubules. ACE2 and NEP generate renoprotective angiotensin (1–7) from angiotensin II and angiotensin I, respectively, and therefore could have a major role in chronic kidne...

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Detalhes bibliográficos
Publicado no:Am J Physiol Renal Physiol
Main Authors: Gutta, Sridevi, Grobe, Nadja, Kumbaji, Meenasri, Osman, Hassan, Saklayen, Mohammad, Li, Gengxin, Elased, Khalid M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6139527/
https://ncbi.nlm.nih.gov/pubmed/29561187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00565.2017
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