Increased urinary angiotensin converting enzyme 2 and neprilysin in patients with type 2 diabetes

Angiotensin converting enzyme 2 (ACE2) and neprilysin (NEP) are metalloproteases that are highly expressed in the renal proximal tubules. ACE2 and NEP generate renoprotective angiotensin (1–7) from angiotensin II and angiotensin I, respectively, and therefore could have a major role in chronic kidne...

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Bibliografske podrobnosti
izdano v:Am J Physiol Renal Physiol
Main Authors: Gutta, Sridevi, Grobe, Nadja, Kumbaji, Meenasri, Osman, Hassan, Saklayen, Mohammad, Li, Gengxin, Elased, Khalid M.
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2018
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6139527/
https://ncbi.nlm.nih.gov/pubmed/29561187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00565.2017
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