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What Is the Impact of Phosphorylation on the Mass Spectrometry Quantification of Intact Phosphoproteins?

Protein phosphorylation is a ubiquitous and critical post-translational modification (PTM) involved in numerous cellular processes. Mass spectrometry (MS)-based proteomics has emerged as the preferred technology for protein identification, characterization, and quantification. Whereas ionization/det...

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Bibliographic Details
Published in:Anal Chem
Main Authors: Wu, Zhijie, Tiambeng, Timothy N., Cai, Wenxuan, Chen, Bifan, Lin, Ziqing, Gregorich, Zachery R., Ge, Ying
Format: Artigo
Language:Inglês
Published: 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6138620/
https://ncbi.nlm.nih.gov/pubmed/29565561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.7b05246
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