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Autophagy mediates SUMO-induced degradation of a polyglutamine protein ataxin-3
Previously, we reported that small ubiquitin-like modifier-1 (SUMO-1) promotes the degradation of a polyglutamine (polyQ) protein ataxin-3 and proposed that proteasomes mediate the proteolysis. Here, we present evidence that autophagy is also responsible for SUMO-induced degradation of this polyQ pr...
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| Veröffentlicht in: | Anim Cells Syst (Seoul) |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Taylor & Francis
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6138331/ https://ncbi.nlm.nih.gov/pubmed/30460066 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19768354.2017.1330765 |
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