Large-Scale Screen for Modifiers of Ataxin-3-Derived Polyglutamine-Induced Toxicity in Drosophila

Polyglutamine (polyQ) diseases represent a neuropathologically heterogeneous group of disorders. The common theme of these disorders is an elongated polyQ tract in otherwise unrelated proteins. So far, only symptomatic treatment can be applied to patients suffering from polyQ diseases. Despite exten...

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Autores principales: Voßfeldt, Hannes, Butzlaff, Malte, Prüßing, Katja, Ní Chárthaigh, Róisín-Ana, Karsten, Peter, Lankes, Anne, Hamm, Sabine, Simons, Mikael, Adryan, Boris, Schulz, Jörg B., Voigt, Aaron
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3489908/
https://ncbi.nlm.nih.gov/pubmed/23139745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0047452
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