लोड हो रहा है...
Polyglutamine Tract Expansion Increases S-Nitrosylation of Huntingtin and Ataxin-1
Expansion of the polyglutamine (polyQ) tract in the huntingtin (Htt) protein causes Huntington’s disease (HD), a fatal inherited movement disorder linked to neurodegeneration in the striatum and cortex. S-nitrosylation and S-acylation of cysteine residues regulate many functions of cytosolic protein...
में बचाया:
| में प्रकाशित: | PLoS One |
|---|---|
| मुख्य लेखकों: | , , , , , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Public Library of Science
2016
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5033456/ https://ncbi.nlm.nih.gov/pubmed/27658206 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0163359 |
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