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Polyglutamine Tract Expansion Increases S-Nitrosylation of Huntingtin and Ataxin-1
Expansion of the polyglutamine (polyQ) tract in the huntingtin (Htt) protein causes Huntington’s disease (HD), a fatal inherited movement disorder linked to neurodegeneration in the striatum and cortex. S-nitrosylation and S-acylation of cysteine residues regulate many functions of cytosolic protein...
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| Yayımlandı: | PLoS One |
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| Asıl Yazarlar: | , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Public Library of Science
2016
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5033456/ https://ncbi.nlm.nih.gov/pubmed/27658206 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0163359 |
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