Sphingosine 1-phosphate is a ligand for peroxisome proliferator-activated receptor-γ that regulates neoangiogenesis

Sphingosine 1-phosphate (S1P) is a bioactive lipid that can function both extracellularly and intracellularly to mediate a variety of cellular processes. Using lipid affinity matrices and a radiolabeled lipid binding assay, we reveal that S1P directly interacts with the transcription factor peroxiso...

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Dades bibliogràfiques
Publicat a:FASEB J
Autors principals: Parham, Kate A., Zebol, Julia R., Tooley, Katie L., Sun, Wai Y., Moldenhauer, Lachlan M., Cockshell, Michaelia P., Gliddon, Briony L., Moretti, Paul A., Tigyi, Gabor, Pitson, Stuart M., Bonder, Claudine S.
Format: Artigo
Idioma:Inglês
Publicat: Federation of American Societies for Experimental Biology 2015
Matèries:
Research Communication
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6137673/
https://ncbi.nlm.nih.gov/pubmed/25985799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.14-261289
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