Sphingosine 1-phosphate is a ligand for peroxisome proliferator-activated receptor-γ that regulates neoangiogenesis

Sphingosine 1-phosphate (S1P) is a bioactive lipid that can function both extracellularly and intracellularly to mediate a variety of cellular processes. Using lipid affinity matrices and a radiolabeled lipid binding assay, we reveal that S1P directly interacts with the transcription factor peroxiso...

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Veröffentlicht in:FASEB J
Hauptverfasser: Parham, Kate A., Zebol, Julia R., Tooley, Katie L., Sun, Wai Y., Moldenhauer, Lachlan M., Cockshell, Michaelia P., Gliddon, Briony L., Moretti, Paul A., Tigyi, Gabor, Pitson, Stuart M., Bonder, Claudine S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Federation of American Societies for Experimental Biology 2015
Schlagworte:
Research Communication
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6137673/
https://ncbi.nlm.nih.gov/pubmed/25985799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.14-261289
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