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An oncogenic role for sphingosine kinase 2
While both human sphingosine kinases (SK1 and SK2) catalyze the generation of the pleiotropic signaling lipid sphingosine 1-phosphate, these enzymes appear to be functionally distinct. SK1 has well described roles in promoting cell survival, proliferation and neoplastic transformation. The roles of...
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| Published in: | Oncotarget |
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| Main Authors: | , , , , , , , , , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Impact Journals LLC
2016
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5323123/ https://ncbi.nlm.nih.gov/pubmed/27588496 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11714 |
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