IFN-γ promotes τ phosphorylation without affecting mature tangles

Inflammatory activation precedes and correlates with accumulating τ lesions in Alzheimer’s disease and tauopathies. However, the relationship between neuroinflammation and etiology of pathologic τ remains elusive. To evaluate whether inflammatory signaling may promote or accelerate neurofibrillary t...

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Publicat a:FASEB J
Autors principals: Li, Andrew, Ceballos-Diaz, Carolina, DiNunno, Nadia, Levites, Yona, Cruz, Pedro E., Lewis, Jada, Golde, Todd E., Chakrabarty, Paramita
Format: Artigo
Idioma:Inglês
Publicat: Federation of American Societies for Experimental Biology 2015
Matèries:
Research Communication
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6137542/
https://ncbi.nlm.nih.gov/pubmed/26156074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.15-275834
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