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Enantioselective fluorination of homoallylic alcohols enabled by the tuning of non-covalent interactions

The study of the enantioselective fluorination of homoallylic alcohols via chiral anion phase transfer (CAPT) catalysis using an in situ generated directing group is described. Multivariate correlation analysis, including designer π-interaction derived parameters, revealed key structural features af...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Coelho, Jaime A. S., Matsumoto, Akira, Orlandi, Manuel, Hilton, Margaret J., Sigman, Matthew S., Toste, F. Dean
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6137454/
https://ncbi.nlm.nih.gov/pubmed/30310638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8sc02223b
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