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Mechanistic Investigations of the Pd(0)-Catalyzed Enantioselective 1,1-Diarylation of Benzyl Acrylates

A mechanistic study of the Pd-catalyzed enantioselective 1,1-diarylation of benzyl acrylates that is facilitated by a Chiral Anion Phase Transfer (CAPT) process is presented. Kinetic analysis, labeling, competition and non-linear effect experiments confirm the hypothesized general mechanism and reve...

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Veröffentlicht in:J Am Chem Soc
Hauptverfasser: Orlandi, Manuel, Hilton, Margaret J., Yamamoto, Eiji, Toste, F. Dean, Sigman, Matthew S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5649438/
https://ncbi.nlm.nih.gov/pubmed/28800230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b06917
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