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Palladium-Catalyzed Enantioselective Redox-Relay Heck Arylation of 1,1-Disubstituted Homoallylic Alcohols

An enantioselective redox-relay oxidative Heck arylation of 1,1-disubstituted alkenes to construct β-stereocenters was developed using a new pyridyloxazoline ligand. Various 1,2-diaryl carbonyl compounds were readily obtained in moderate yield and good to excellent enantioselectivity. Additionally,...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Chen, Zhi-Min, Hilton, Margaret J., Sigman, Matthew S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5039009/
https://ncbi.nlm.nih.gov/pubmed/27571167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b06994
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