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Antibody–nucleotide conjugate as a substrate for DNA polymerases
Here we report on the development of an antibody-modified nucleotide and its sequence-selective incorporation into nascent DNA catalysed by DNA polymerases. Although the modification of the nucleotide is several orders of magnitude larger than the natural dNTP substrate and even exceeds the size of...
Guardat en:
| Publicat a: | Chem Sci |
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| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Royal Society of Chemistry
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6137436/ https://ncbi.nlm.nih.gov/pubmed/30310633 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8sc01839a |
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