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Antibody–nucleotide conjugate as a substrate for DNA polymerases
Here we report on the development of an antibody-modified nucleotide and its sequence-selective incorporation into nascent DNA catalysed by DNA polymerases. Although the modification of the nucleotide is several orders of magnitude larger than the natural dNTP substrate and even exceeds the size of...
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| Udgivet i: | Chem Sci |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Royal Society of Chemistry
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6137436/ https://ncbi.nlm.nih.gov/pubmed/30310633 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8sc01839a |
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