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Therminator DNA Polymerase: Modified Nucleotides and Unnatural Substrates
A variant of 9°N DNA polymerase [Genbank ID (AAA88769.1)] with three mutations (D141A, E143A, A485L) and commercialized under the name “Therminator DNA polymerase” has the ability to incorporate a variety of modified nucleotide classes. This Review focuses on how Therminator DNA Polymerase has enabl...
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| 發表在: | Front Mol Biosci |
|---|---|
| Main Authors: | , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Frontiers Media S.A.
2019
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6491775/ https://ncbi.nlm.nih.gov/pubmed/31069234 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2019.00028 |
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