Use of cationic microbubbles targeted to P-selectin to improve ultrasound-mediated gene transfection of hVEGF(165) to the ischemic myocardium

Gene therapies have been applied to the treatment of cardiovascular disease, but their use is limited by the need to deliver them to the right target. We have employed targeted contrast ultrasound-mediated gene transfection (TCUMGT) via ultrasound-targeted microbubble destruction (UTMD) to transfer...

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Publicado no:J Zhejiang Univ Sci B
Main Authors: Shentu, Wei-hui, Yan, Cao-xin, Liu, Chun-mei, Qi, Rui-xiang, Wang, Yao, Huang, Zhao-xu, Zhou, Li-ming, You, Xiang-dong
Formato: Artigo
Idioma:Inglês
Publicado em: Zhejiang University Press 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6137414/
https://ncbi.nlm.nih.gov/pubmed/30178636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1631/jzus.B1700298
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