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Ultrasound-Mediated Gene Delivery with Cationic Versus Neutral Microbubbles: Effect of DNA and Microbubble Dose on In Vivo Transfection Efficiency

Objective: To assess the effect of varying microbubble (MB) and DNA doses on the overall and comparative efficiencies of ultrasound (US)-mediated gene delivery (UMGD) to murine hindlimb skeletal muscle using cationic versus neutral MBs. Materials and Methods: Cationic and control neutral MBs were ch...

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Detalhes bibliográficos
Main Authors: Panje, Cedric M., Wang, David S., Pysz, Marybeth A., Paulmurugan, Ramasamy, Ren, Ying, Tranquart, Francois, Tian, Lu, Willmann, Jürgen K.
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3516840/
https://ncbi.nlm.nih.gov/pubmed/23227124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.4240
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