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ANALYSIS OF IN VITRO TRANSFECTION BY SONOPORATION USING CATIONIC AND NEUTRAL MICROBUBBLES

The objective of the study was to examine the role of acoustic power intensity and microbubble and plasmid concentrations on transfection efficiency in HEK-293 cells using a sonoporator with a 1-MHz transducer. A green fluorescent protein (GFP) reporter plasmid was delivered in as much as 80% of tre...

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Detalhes bibliográficos
Main Authors: Tlaxca, Jose L., Anderson, Christopher R., Klibanov, Alexander L., Lowrey, Bryce, Hossack, John A., Alexander, J. Steven, Lawrence, Michael B., Rychak, Joshua J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2996233/
https://ncbi.nlm.nih.gov/pubmed/20800945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ultrasmedbio.2010.05.014
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