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Targeted gene transfection from microbubbles into vascular smooth muscle cells using focused, ultrasound-mediated delivery

We investigate a method for gene delivery to vascular smooth muscle cells using ultrasound triggered delivery of plasmid DNA from electrostatically coupled cationic microbubbles. Microbubbles carrying reporter plasmid DNA were acoustically ruptured in the vicinity of smooth muscle cells in vitro und...

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Bibliografiska uppgifter
Huvudupphovsmän: Phillips, Linsey C., Klibanov, Alexander L., Wamhoff, Brian R., Hossack, John A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2010
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2930891/
https://ncbi.nlm.nih.gov/pubmed/20800174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ultrasmedbio.2010.06.010
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