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Focused in vivo Delivery of Plasmid DNA to the Porcine Vascular Wall via Intravascular Ultrasound Destruction of Microbubbles

BACKGROUND: Safety concerns associated with drug-eluting stents have spurred interest in alternative vessel therapeutics following angioplasty. Microbubble contrast agents have been shown to increase gene transfection in vivo in the presence of ultrasound. Objectives/Methods: The purpose of this stu...

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Detalhes bibliográficos
Main Authors: Phillips, Linsey C., Klibanov, Alexander L., Bowles, Douglas K., Ragosta, Michael, Hossack, John A., Wamhoff, Brian R.
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2865392/
https://ncbi.nlm.nih.gov/pubmed/19923850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000258905
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