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Localized In Vivo Model Drug Delivery with Intravascular Ultrasound and Microbubbles

An intravascular ultrasound (IVUS) and microbubble drug delivery system was evaluated in both ex vivo and in vivo swine vessel models. Microbubbles with the fluorophore DiI embedded in the shell as a model drug were infused into ex vivo swine arteries at a physiological flow rate (105 mL/min) while...

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Détails bibliographiques
Publié dans:Ultrasound Med Biol
Auteurs principaux: Kilroy, Joseph P., Klibanov, Alexander L., Wamhoff, Brian R., Bowles, Douglas K., Hossack, John A.
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4400670/
https://ncbi.nlm.nih.gov/pubmed/25130449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ultrasmedbio.2014.04.007
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