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Localized In Vivo Model Drug Delivery with Intravascular Ultrasound and Microbubbles

An intravascular ultrasound (IVUS) and microbubble drug delivery system was evaluated in both ex vivo and in vivo swine vessel models. Microbubbles with the fluorophore DiI embedded in the shell as a model drug were infused into ex vivo swine arteries at a physiological flow rate (105 mL/min) while...

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Bibliographic Details
Published in:Ultrasound Med Biol
Main Authors: Kilroy, Joseph P., Klibanov, Alexander L., Wamhoff, Brian R., Bowles, Douglas K., Hossack, John A.
Format: Artigo
Language:Inglês
Published: 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4400670/
https://ncbi.nlm.nih.gov/pubmed/25130449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ultrasmedbio.2014.04.007
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