Reducing Neointima Formation in a Swine Model with IVUS and Sirolimus Microbubbles

Potent therapeutic compounds with dose dependent side effects require more efficient and selective drug delivery to reduce systemic drug doses. Here, we demonstrate a new platform that combines intravascular ultrasound (IVUS) and drug-loaded microbubbles to enhance and localize drug delivery, while...

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Udgivet i:Ann Biomed Eng
Main Authors: Kilroy, Joseph P., Dhanaliwala, Ali H., Klibanov, Alexander L., Bowles, Douglas K., Wamhoff, Brian R., Hossack, John A.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4609231/
https://ncbi.nlm.nih.gov/pubmed/25893508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10439-015-1315-6
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