Use of cationic microbubbles targeted to P-selectin to improve ultrasound-mediated gene transfection of hVEGF(165) to the ischemic myocardium

Gene therapies have been applied to the treatment of cardiovascular disease, but their use is limited by the need to deliver them to the right target. We have employed targeted contrast ultrasound-mediated gene transfection (TCUMGT) via ultrasound-targeted microbubble destruction (UTMD) to transfer...

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Veröffentlicht in:J Zhejiang Univ Sci B
Hauptverfasser: Shentu, Wei-hui, Yan, Cao-xin, Liu, Chun-mei, Qi, Rui-xiang, Wang, Yao, Huang, Zhao-xu, Zhou, Li-ming, You, Xiang-dong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Zhejiang University Press 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6137414/
https://ncbi.nlm.nih.gov/pubmed/30178636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1631/jzus.B1700298
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