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Abemaciclib, a Selective CDK4/6 Inhibitor Enhances the Radiosensitivity of Non-Small Cell Lung Cancer in vitro and in vivo
PURPOSE: To characterize the ionizing radiation (IR) enhancing effects and underlying mechanisms of CDK4/6 inhibitor, Abemaciclib in Non–Small Cell Lung Cancer cells (NSCLC) in vitro and in vivo. EXPERIMENTAL DESIGN: IR enhancement by Abemaciclib in a variety of NSCLC cell lines was assessed by in v...
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| Publicado no: | Clin Cancer Res |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6137329/ https://ncbi.nlm.nih.gov/pubmed/29716919 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-17-3575 |
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