Investigating the role of mGluR2 versus mGluR3 in antipsychotic-like effects, sleep-wake architecture and network oscillatory activity using novel Han Wistar rats lacking mGluR2 expression

Group II metabotropic glutamate receptors (mGluR2 and mGluR3) are implicated in a number of psychiatric disorders. They also control sleep-wake architecture and may offer novel therapeutic targets. However, the roles of the mGluR2 versus mGluR3 subtypes are not well understood. Here, we have taken a...

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Publicado no:Neuropharmacology
Main Authors: Wood, Christian M., Wafford, Keith A., McCarthy, Andrew P., Hewes, Nicola, Shanks, Elaine, Lodge, David, Robinson, Emma S.J.
Formato: Artigo
Idioma:Inglês
Publicado em: Pergamon Press 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6137075/
https://ncbi.nlm.nih.gov/pubmed/30005976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2018.07.013
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