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Pretreatment with mGluR2 or mGluR3 Agonists Reduces Apoptosis Induced by Hypoxia-Ischemia in Neonatal Rat Brains

Hypoxia-ischemia (HI) in an immature brain results in energy depletion and excessive glutamate release resulting in excitotoxicity and oxidative stress. An increase in reactive oxygen species (ROS) production induces apoptotic processes resulting in neuronal death. Activation of group II mGluR was s...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Bratek - Gerej, Ewelina, Bronisz, Agnieszka, Ziembowicz, Apolonia, Salinska, Elzbieta
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7963909/
https://ncbi.nlm.nih.gov/pubmed/33763176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2021/8848015
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