Pretreatment with mGluR2 or mGluR3 Agonists Reduces Apoptosis Induced by Hypoxia-Ischemia in Neonatal Rat Brains

Hypoxia-ischemia (HI) in an immature brain results in energy depletion and excessive glutamate release resulting in excitotoxicity and oxidative stress. An increase in reactive oxygen species (ROS) production induces apoptotic processes resulting in neuronal death. Activation of group II mGluR was s...

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Publicado en:Oxid Med Cell Longev
Autores principales: Bratek - Gerej, Ewelina, Bronisz, Agnieszka, Ziembowicz, Apolonia, Salinska, Elzbieta
Formato: Artigo
Lenguaje:Inglês
Publicado: Hindawi 2021
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7963909/
https://ncbi.nlm.nih.gov/pubmed/33763176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2021/8848015
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