PKR and GCN2 stress kinases promote an ER stress-independent eIF2α phosphorylation responsible for calreticulin exposure in melanoma cells

The immunogenic cell death (ICD) process represents a novel therapeutic approach to treat tumours, in which cytotoxic compounds promote both cancer cell death and the emission of damage-associated molecular patterns (DAMPs) from dying cells, to activate the immune system against the malignancy. Ther...

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Detalles Bibliográficos
Publicado en:Oncoimmunology
Main Authors: Giglio, Paola, Gagliardi, Mara, Tumino, Nicola, Antunes, Fernanda, Smaili, Soraya, Cotella, Diego, Santoro, Claudio, Bernardini, Roberta, Mattei, Maurizio, Piacentini, Mauro, Corazzari, Marco
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2018
Assuntos:
Original Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6136861/
https://ncbi.nlm.nih.gov/pubmed/30221067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2018.1466765
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