Shugoshin 1 is dislocated by KSHV-encoded LANA inducing aneuploidy

Shugoshin-1 (Sgo1) protects the integrity of the centromeres, and H2A phosphorylation is critical for this process. The mitotic checkpoint kinase Bub1, phosphorylates H2A and ensures fidelity of chromosome segregation and chromosome number. Oncogenic KSHV induces genetic alterations through chromoso...

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Detaylı Bibliyografya
Yayımlandı:PLoS Pathog
Asıl Yazarlar: Lang, Fengchao, Sun, Zhiguo, Pei, Yonggang, Singh, Rajnish Kumar, Jha, Hem Chandra, Robertson, Erle S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2018
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6136811/
https://ncbi.nlm.nih.gov/pubmed/30212568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007253
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