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Structural basis for ubiquitin-mediated antiviral signal activation by RIG-I
Ubiquitin (Ub) has important roles in a wide range of intracellular signalling pathways. In the conventional view, ubiquitin alters the signalling activity of the target protein through covalent modification, but accumulating evidence points to the emerging role of non-covalent interaction between u...
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| Veröffentlicht in: | Nature |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6136653/ https://ncbi.nlm.nih.gov/pubmed/24590070 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13140 |
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