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Molecular imprinting as a signal activation mechanism of the viral RNA sensor RIG-I
RIG-I activates interferon signaling pathways by promoting filament formation of the adaptor molecule, MAVS. Assembly of the MAVS filament is mediated by its CARD domain (CARD(MAVS)) and requires its interaction with the tandem CARDs of RIG-I (2CARD(RIG-I)). However, the precise nature of the intera...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4142144/ https://ncbi.nlm.nih.gov/pubmed/25018021 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2014.06.010 |
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